Epithalon

Epithalon (CAS 307297-39-8), also known as Epitalon or Epithalone, is a synthetic tetrapeptide with the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Defined by the amino acid sequence Ala-Glu-Asp-Gly, Epithalon was synthesised based on the amino acid composition of Epithalamin, a polypeptide preparation originally derived from bovine pineal tissue. Developed at the Saint Petersburg Institute of Bioregulation and Gerontology, it belongs to a class of short synthetic peptides investigated as bioregulators in the Russian scientific literature. Produced via solid-phase peptide synthesis, Epithalon is associated with telomerase-related signalling and pineal gland neuroendocrine pathways in preclinical gerontology research