KPV is a highly active tripeptide (Lysine-Proline-Valine) representing the C-terminal fragment of alpha-melanocyte-stimulating hormone. Renowned in immunobiology research, KPV is investigated for its powerful anti-inflammatory and antimicrobial properties, acting to suppress NF-kB pathways in vitro.
“The tripeptide sequence of KPV retains the core immunomodulatory signaling of alpha-MSH, offering a highly stable template for evaluating cell recovery during inflammatory stress.”
Detailed molecular data is cataloged at NCBI at the NCBI Melanocortin Portal and peer-reviewed journals are searchable at PubMed KPV Peptide Collection for advanced cellular immunology research. It works by blocking cytolytic transcription factor cascades.
Key Areas of Investigation:
- NF-kB Pathway Inhibition: Investigating intracellular transcription factor blockades.
- Antimicrobial Efficacy: Preclinical assays on cellular defense against Candida albicans.
- Intestinal Inflammation Integrity: Studies on epithelial cell barrier restoration in vitro.
This material is supplied exclusively as a lyophilized solid for laboratory research and analytical evaluation, and is strictly not for human or therapeutic use.




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